Modified Nucleic Acids
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Beschreibung
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases.Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Summarizes the latest studies in modified nucleic acid research Spans various aspects of modified nucleic acids, from their chemical synthesis to the in vivo application Written by internationally respected experts
Autor*in
Kazuhiko Nakatani
Themen in »Modified Nucleic Acids«
Pyrimidine and purine analogs Electron paramagnetic resonance (EPR) spectroscopy Emission paramagnetic resonance spectroscopy Double-stranded DNA Unnatural nucleic acids Base pair creation Nucleobases biochemical engineering