This book provides a broad overview of pancreatic neuroendocrine neoplasms, focusing on the most important developments in the technologies used to diagnose, classify, and treat them. After a historical and epidemiological overview, the opening chapters examine the various diagnostic approaches (radiology, nuclear medicine, endocrinology, cytology, and immunohistochemistry) and discuss the WHO classification. The functioning and nonfunctioning tumor types are then fully discussed, covering epidemiology, diagnosis, morphology, and prognosis of each entity. Careful consideration is given to the molecular features that have contributed in understanding the pathogenesis of such neoplasms and may have potential implications for the diagnostic and therapeutic pathways. The final chapters consider the surgical and medical approaches to therapy, providing a practical and analytical overview of the available options. The book is written by a multidisciplinary team of worldwide-recognized experts and is addressed to radiologists, nuclear medicine physicians, endocrinologists, pathologists, surgeons, and oncologists.
This book provides a broad overview of pancreatic neuroendocrine neoplasms, focusing on the most important developments in the technologies used to diagnose, classify and treat them. After a historical and epidemiological overview, the opening chapters examine the various diagnostic approaches (radiology, nuclear medicine, endocrinology, cytology and immunohistochemistry) and discuss the WHO classification. The functioning and nonfunctioning tumor types are then fully discussed, covering epidemiology, diagnosis, morphology and prognosis of each entity. Careful consideration is given to the molecular features that have contributed in understanding the pathogenesis of such neoplasms and may have potential implications for the diagnostic and therapeutic pathways. The final chapters consider the surgical and medical approaches to therapy, providing a practical and analytical overview of the available options. The book is written by a multidisciplinary team of worldwide-recognized experts and is addressed to radiologists, nuclear medicine physicians, endocrinologists, pathologists, surgeons and oncologists.
Offers a modern overview of the diagnosis, classification and therapy of neuroendocrine neoplasms of the pancreas Provides the tools required for correct classification of the different tumor entities Written by a multidisciplinary team of authors
Stefano La Rosa
Diagnostic methods Functioning pancreatic neuroendocrine tumors Nonfunctioning pancreatic neuroendocrine tumors Pharmacological therapy Surgical therapy
“The purpose is to comprehensively present pancreatic neuroendocrine tumors from both a clinical and pathological standpoint. In particular, the book aims to cover the advances in diagnosis and treatment that have occurred over the past decade. This book is written for both clinicians and pathologists who have a particular interest in the management or diagnosis of pancreatic neuroendocrine tumors. Pathology residents or oncology fellows with a particular interest in these tumors also could find this book of value.” (Kyle D. Perry, Doody’s Book Reviews, September, 2015)