Next Generation Sequencing in Cancer Research, Volume 2
From Basepairs to Bedsides
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Beschreibung
Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides, the second in the series “Next Generation Sequencing Technology in Cancer Research—From Basepairs to Bedsides,” is designed to fill the gap between cancer genome research and clinical management of the individual cancer patient. The volume presents the principles of next generation sequencing (NGS) technologies and massively parallel DNA sequencing and their application of the whole genome sequences (WGS), whole exome-seq (WES), RNA-seq, miRNA-seq, and ChIP-seq in cancer research programs and to apply the newly discovered driver genetic alterations for prevention, early diagnosis and genome-oriented precision cancer treatment.
Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides brings together the implementation of a wide range of NGS technologies, including single-cell sequencing, in the clinical setting: discovery and validation of cancer biomarkers; standardization of NGS data production; NGS data reporting systems for clinicians; novel anti-cancer therapies development from NGS data; conducting of clinical trials of newly investigated cancer drugs. It provides compelling evidence to signal a new future for health care and a new standard for cancer care.Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable cancer treatment plan and potential cure is more optimistic now with the unfolding of the cancer genome. The collective knowledge of how to leverage next generation sequencing in cancer research is paving the way. The important information provided in this volume will move the field forward in developing novel targeted cancer therapies.
In-depth coverage of single cell sequencing for cancer Gives bioinformatic tools for cancer genome studies Explores the latest high-throughput sequencing technologies
Autor*in
Wei Wu
Themen in »Next Generation Sequencing in Cancer Research, Volume 2«
RNAs Whole-genome sequencing cancer genomics high-throughput sequencing transcriptome