Correlation Force Spectroscopy for Single Molecule Measurements
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Beschreibung
This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.
This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.
Nominated as an outstanding theses by Virginia Tech Introduces the dynamic new technique for correlation force spectroscopy (CFS) Details the significance of CFS in polymer physics and chemistry Explains the measurement capability in the area of high frequency rheology and single molecule dynamic measurements Includes supplementary material: sn.pub/extras
Autor*in
Milad Radiom
Themen in »Correlation Force Spectroscopy for Single Molecule Measurements«
Atomic Force Microscopy Colloidal Probe Correlation Force Correlation Force Spectroscopy Single Molecule Force Spectroscopy