Diseases of the Cardiac Pump
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Beschreibung
Together, the volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanism. Therefore, investigation of flows of blood and air in anatomical conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning in quantitative terms.
The present volume focuses on macroscopic aspects of the cardiovascular and respiratory systems in pathological conditions, i.e., diseases of the cardiac pump, blood vessels, and airways, as well as their treatments. Only diseases that have a mechanical origin or are associated with mechanical disorders are covered. Local flow disturbances can trigger pathophysiological processes or, conversely, result from diseases of conduit walls or their environment. The ability to model these phenomena is essential to the development and manufacturing of medical devices, which incorporate a stage of numerical tests in addition to experimental procedures.
Together, the volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanism. Therefore, investigation of flows of blood and air in anatomical conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning in quantitative terms.
The present volume focuses on macroscopic aspects of the cardiovascular and respiratory systems in pathological conditions, i.e., diseases of the cardiac pump, blood vessels, and airways, as well as their treatments. Only diseases that have a mechanical origin or are associated with mechanical disorders are covered. Local flow disturbances can trigger pathophysiological processes or, conversely, result from diseases of conduit walls or their environment. The ability to model these phenomena is essential to the development and manufacturing of medical devices, which incorporate a stage of numerical tests in addition to experimental procedures.
Covers cardiac diseases and their main treatment Reviews histological and biochemical data Provides insight into data required for modeling and simulating cardiac electrophysiology and mechanics in diseased hearts as well as into the development of medical devices Includes supplementary material: sn.pub/extras
Autor*in
Marc Thiriet
Themen in »Diseases of the Cardiac Pump«
Acute Lung Injury Aneurysms Aortic Valve Failure Arterial Wall Remodeling Arteriosclerosis Cardiomyopathies Cardiovascular Markers Congenital Heart Defects Cystic Fibrosis Endovascular Therapy Heart Failure Heart Pathologies Heart Valve Failure Hyperoxia Hypertension
Stimmen zu »Diseases of the Cardiac Pump«
“This is a review of macroscopic aspects of diseases of the cardiac pump as well as treatments that could be potential targets for biomechanical studies. … The intended audience includes researchers, practitioners, and students in the fields of medicine and cardiovascular disease who are interested in biomechanical and biomathematical aspects of cardiac diseases. … It is strongly recommended for its intended audience.” (Samit Bhatheja, Doody's Book Reviews, June, 2015)
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