Gene Prioritization
Rationale, Methodologies and Algorithms
Buch in deiner Nähe kaufen
Beschreibung
Identifying causal genes underlying susceptibility to human disease is a problem of primary importance in the post-genomic era and in current biomedical research. Recently, there has been a paradigm shift of such gene-discovery efforts from rare, monogenic conditions to common “oligogenic” or “multifactorial” conditions such as asthma, diabetes, cancers and neurological disorders. These conditions are referred to as multifactorial because, susceptibility to these diseases is attributed to the combinatorial effects of genetic variation at a number of different genes and their interaction with relevant environmental exposures. The goal of this book is to introduce gene prioritization aspects and the candidate gene prioritization algorithms to give readers a comprehensive view on the subject.
Introduces gene prioritization aspects and candidate gene prioritization algorithms to give readers a comprehensive view on the subject
Focuses on gene prioritizations concepts and gene prioritization algorithms
Useful to both biologists and computer scientists to get an idea about the field and serves as a strong starting point for someone who wants to work on gene prioritization methods
Autor*in
Ali Masoudi-Nejad
Themen in »Gene Prioritization«
algorithms gene prioritization post-genome