Functional Ultrastructure
Atlas of Tissue Biology and Pathology
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Beschreibung
This atlas of functional ultrastructure provides a detailed insight into the complex structure and organization of cells and tissues, highlights specific cellular and tissue functions, and the dynamics of diverse intracellular processes. Highly informative electron micrographs are complemented by explanatory texts, selected references and schemes. The concept that subcellular organelles provide the structural foundation for fundamental processes of living organisms is emphasized. The first part covers the cellular organelles and changes due to experiments or occurring under pathological conditions. The second part illustrates by selected examples principles of functional tissue organization and typical changes resulting from experimental induction or pathological situations.
Along with a detailed insight into the complex structure and organization of cells and tissues, this second edition of the atlas also highlights specific cellular and tissue functions, as well as providing the dynamics of diverse intracellular processes.
The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.
It will serve as a handy reference guide for diagnostic and research electron microscopy laboratories in clinical, industrial, and academic settings.
This atlas of functional ultrastructure provides not only a detailed insight into the complex structure and organization of cells and tissues but also into specific functions fulfilled by the various cellular organelles and the dynamics of the different processes inside cells. The large collection of electron micrographs, together with those from immunoelectron microscopy, is complemented by thorough explanations. Emphasis is placed on an integrated view of structure and function. Specialized cell types from the various tissues, and principles of tissue organization are presented. Under various conditions of disease, characteristic structural alterations may occur which is illustrated by examples.
Autor*in
Margit Pavelka
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Endoplasmatisches Reticulum Glycogen RNA biosynthesis cell architecture cell biology cell nucleus cells electron microscopy histology matrix proteins tissue ultrastructural pathology ultrastructure
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"... I recommend this atlas to all students of biology and pathology but especially those people buying for a university / TAFE library where students or researchers will be using this text." Australian Journal of Medical Science 2/2006, vol. 27, No. 1
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