The rapid pace of evolution in domino, or cascadebased transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals.
x „Science of Synthesis: Applications of Domino Transformations in Organic Synthesis“ explores the topic thoroughly and systematically, serving as the basis for practical applications and future research
x The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being
accomplished within a single reaction vessel
x The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation,
radical chemistry, or an acid-induced cascade among many others
x Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements
x Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds
Scott A. Snyder
C-H Activation C-H Aktivierung Organic Chemistry Organic Synthesis Organic Transformation Organische Chemie Organische Synthese Reference Work Synthetic Methods