The two-volume set on C-1 Building Blocks in Organic
Synthesis critically reviews the state of the art of a wide variety of reactions
by which one carbon atom is added to an organic molecule, forming a C-C bond. In
spite of the numerous classic reactions of this kind, there has been enormous
progress in recent years, especially for those reactions involving catalytic
methods. Introduction of substituted methyl groups is a major challenge and only
very recently the first catalysts have been discovered that enable the
introduction of fluoromethyl groups in aromatics.
Piet W.N.M. van Leeuwen
IMINES TRIFLUOROMETHYLATION VILSMEIER REAGENT METATHESIS OXIDATIVE COUPLING FORMALDEHYDE METHODS IN ORGANIC SYNTHESIS CYANATION CROSS COUPLING METHODS ORGANOMETALLIC REAGENTS CARBONYLATION OXETANES METHOD KHARASCH REACTION TEBBE