The Special Issue on “Model-Based Tools for Pharmaceutical Manufacturing Processes” will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.
Krist V. Gernaey
pharmaceutical processes flexibility analysis probabilistic design space global optimization model integration flowsheet modeling sensitivity analysis continuous manufacturing wet granulation Amoxicillin enzymatic synthesis non-isothermal modelling parameter estimation dynamic optimisation enzymatic reaction