In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.
Andrew J. Larner
diagnosis dementia mild cognitive impairment Mini-Addenbrooke’s Cognitive Examination Codex decision tree dementia Free-Cog MoCA mild cognitive impairment sensitivity and specificity Alzheimer’s disease diagnostic imaging molecular imaging precision medicine