MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.
Discusses the diagnostic potential of circulating MicroRNAs
Presents hypotheses on the potential biological relevance of circulating microRNAs
Highlights the role of circulating microRNAs in epigenetics, tumor surveillance and interindvidual communication
Peter Igaz
circulating microRNA early diagnosis microRNA disease diagnostics minimally invasive diagnosis disease marker epigenetic mediators biological relevance gene expression