Genomics of Pattern Recognition Receptors
Applications in Oncology and Cardiovascular Diseases
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Beschreibung
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Summarizes the field and indicates key directions Explores and analyzes genomic variations With numerous tables presenting the data systematically Includes supplementary material: sn.pub/extras
Autor*in
Anton G. Kutikhin
Themen in »Genomics of Pattern Recognition Receptors«
Cancer Cardiovascular diseases Immune response NOD-like receptors Pathogen-associated patterns Toll-like receptors Receptors
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From the reviews:
“This book comprehensively covers the polymorphism of genes-encoding pattern recognition receptors (PRRs) … . The book is intended for immunologists, cancer researchers, cardiologists, epidemiologists, microbiologists, and geneticists, as well as PhD, graduate, and undergraduate students of biomedical faculties and their lecturers. This is a unique book that analyzes the field of PRR genomics and its practical applications. … This book will be quite useful for a very wide audience.” (Omer Iqbal, Doody’s Book Reviews, March, 2014)
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