Modern Heterocyclic Chemistry
Structure–Electronic Property–Mechanistic Aspects
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Beschreibung
This book provides a systematic and comprehensive treatment of the structures, syntheses, and reaction processes of heterocyclic compounds containing nitrogen, oxygen, and sulfur. Unsaturated heterocyclic systems ranging from three-membered to seven-membered rings are examined with emphasis on their physical and spectroscopic properties, natural occurrence, biological activities, and synthetic methodologies
The text begins with molecular physical and spectroscopic data, followed by discussions of the occurrence and biological activities of natural and synthetic heterocyclic compounds. Synthetic methods and reaction mechanisms are analyzed in detail, with particular attention given to fundamental reactions and structure–reactivity relationships. Compounds possessing the same ring framework but different heteroatoms are compared systematically, highlighting both their similarities and their structural and reactivity differences.
Following the discussion of synthesis and mechanisms, the reactions of the corresponding heterocyclic compounds are examined in a systematic manner. Monocyclic heterocycles fused with a benzene ring at different positions are also treated comparatively and systematically.
Heterocyclic compounds play a central role in modern chemistry, particularly in pharmaceutical research and materials science. Many biologically active molecules, therapeutic agents, and functional materials contain heterocyclic frameworks. This book is intended to provide students and researchers with a solid understanding of the synthesis, reactivity, and applications of heterocyclic compounds.
Target audience: Undergraduate, graduate, and doctoral students in chemistry; pharmacy and chemical engineering students; researchers; medicinal chemists; and pharmaceutical scientists.
This book provides a systematic and comprehensive treatment of the structures, syntheses, and reaction processes of heterocyclic compounds containing nitrogen, oxygen, and sulfur. Unsaturated heterocyclic systems ranging from three-membered to seven-membered rings are examined with emphasis on their physical and spectroscopic properties, natural occurrence, biological activities, and synthetic methodologies
The text begins with molecular physical and spectroscopic data, followed by discussions of the occurrence and biological activities of natural and synthetic heterocyclic compounds. Synthetic methods and reaction mechanisms are analyzed in detail, with particular attention given to fundamental reactions and structure–reactivity relationships. Compounds possessing the same ring framework but different heteroatoms are compared systematically, highlighting both their similarities and their structural and reactivity differences.
Following the discussion of synthesis and mechanisms, the reactions of the corresponding heterocyclic compounds are examined in a systematic manner. Monocyclic heterocycles fused with a benzene ring at different positions are also treated comparatively and systematically.
Heterocyclic compounds play a central role in modern chemistry, particularly in pharmaceutical research and materials science. Many biologically active molecules, therapeutic agents, and functional materials contain heterocyclic frameworks. This book is intended to provide students and researchers with a solid understanding of the synthesis, reactivity, and applications of heterocyclic compounds.
Target audience: Undergraduate, graduate, and doctoral students in chemistry; pharmacy and chemical engineering students; researchers; medicinal chemists; and pharmaceutical scientists.
Comprehensive guide to structures, syntheses, and reactivity of N-, O-, and S-heterocycles Systematic comparisons across ring sizes and heteroatoms, with spectra, bioactivity, and methods Clear focus on reactions, mechanisms, and applications in pharma and materials science
Autor*in
Metin Balcı
Themen in »Modern Heterocyclic Chemistry«
Advanced heterocyclic chemistry Synthetic methodologies in heterocyclic chemistry Mechanistic insights into heterocyclic formation Role of heterocyclic scaffolds in medicinal chemistry Bioactive natural products containing heterocycles Structural diversity of heterocyclic ring systems Spectroscopic characterization of heterocyclic molecules Comparative analysis of nitrogen oxygen and sulfur heterocycles Functionalization of heterocyclic ring systems