Amorphous Solid Dispersions
A Comprehensive Guide to Theory, Manufacturing, Processing, Regulatory Status and Clinical Translation
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Beschreibung
The book provides a comprehensive overview of pharmaceutical amorphous and co-amorphous solid dispersions, covering topics ranging from fundamentals to preparation approaches. It covers principles of ASD formation and the role of molecular interactions, preparation methodology and formulation challenges, characterization methods, physicochemical stability and regulatory aspects. This book is intended for pharmaceutical formulation scientists and researchers, as well as students and academics with interest in the broader area of solid pharmaceutics.
The book provides a comprehensive overview of pharmaceutical amorphous and co-amorphous solid dispersions, covering topics ranging from fundamentals to preparation approaches. It covers principles of ASD formation and the role of molecular interactions, preparation methodology and formulation challenges, characterization methods, physicochemical stability and regulatory aspects. This book is intended for pharmaceutical formulation scientists and researchers, as well as students and academics with interest in the broader area of solid pharmaceutics.
Offers coverage of all aspects of pharmaceutical amorphous solid dispersions, from fundamentals to future perspectives Provides cutting-edge technology and reports the latest research findings, techniques, and advancements in the field Presents insights and guidance on various preparation techniques, characterization methods, and regulation
Autor*in
Ioannis Nikolakakis
Themen in »Amorphous Solid Dispersions«
Amorphous solid dispersions ASD preparation techniques Polymer-based ASDs Co-amorphous systems In-vitro/in-vivo correlations Molecular simulations in ASDs Stability of ASDs Regulatory aspects of ASDs Commercialization of ASDs Thermal Approaches for Preparation of ASDs Mechanical Approaches for the Preparation of ASDs Mesoporous–based Amorphous Solid Dispersions High Drug Loading Amorphous Solid Dispersions Structural Characterization of ASDs Molecular Simulations in the Prediction of ASDs