Biology of Bladder Cancer
From Molecular Insights to Clinical Strategies
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Beschreibung
This book provides an update on the current understanding of various aspects of bladder cancer biology and introduces clinical manifestations together with current and novel treatment aspects.
Key concepts covered include epidemiology and genetic predisposition to bladder cancer, insights into the mutational events and molecular pathogenesis of bladder cancer, detailed analyses of tumor subtypes, and references to common experimental models used in the study of bladder cancer. The book addresses critical issues such as the molecular features that contribute to the development of bladder cancer, the impact of the tumor microenvironment on disease progression, and the potential of novel urine- and blood-based biomarkers for diagnosis and treatment. Innovative therapeutic applications are also explored, including targeting immune checkpoints and personalized medicine approaches.
Aimed at early career and experienced researchers or clinicians alike, this volume provides an interdisciplinary understanding of bladder cancer. Delving into the biology, pathology, and clinical aspects of the disease, it serves as an indispensable resource for understanding bladder cancer's complexity.
This book provides an update on the current understanding of various aspects of bladder cancer biology and introduces clinical manifestations together with current and novel treatment aspects.
Key concepts covered include epidemiology and genetic predisposition to bladder cancer, insights into the mutational events and molecular pathogenesis of bladder cancer, detailed analyses of tumor subtypes, and references to common experimental models used in the study of bladder cancer. The book addresses critical issues such as the molecular features that contribute to the development of bladder cancer, the impact of the tumor microenvironment on disease progression, and the potential of novel urine- and blood-based biomarkers for diagnosis and treatment. Innovative therapeutic applications are also explored, including targeting immune checkpoints and personalized medicine approaches.
Aimed at early career and experienced researchers or clinicians alike, this volume provides an interdisciplinary understanding of bladder cancer. Delving into the biology, pathology, and clinical aspects of the disease, it serves as an indispensable resource for understanding bladder cancer's complexity.
Discusses the molecular pathogenesis of bladder cancer Highlights experimental models to study bladder cancer Outlines therapeutic approaches based on the molecular understanding of bladder cancer
Autor*in
Margaret A. Knowles
Themen in »Biology of Bladder Cancer«
Cell Cycle Regulation DNA Methylation DNA Repair Genes Immune Checkpoint Metastasis MIBC Muscle Invasive Bladder Cancer NMIBC Non-Muscle Invasive Bladder Cancer Oncogenic Drivers PDX Models Tumor Microenvironment Urothelium Urine Biomarker Urothelial Cancer