Striessnig Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease

Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease

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Beschreibung

The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.


Provides state-of the art insight into current research on voltage-gared Ca2+ channels Broadens the understanding of how Ca2+ channelopathies can provide novel insight into therapies of rare diseases Discusses concepts of the regulation of Ca2+ channels by neurotransmitters, enzymes and drugs

Autor*in

Jörg Striessnig

Themen in »Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease«

Ca2+ channels Ca2+ channelopathies Ca2+ channel blockers channel-interacting proteins therapies of rare diseases

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Details

ISBN: 9783031384394
Verlag: Springer International Publishing
Erscheinung: 02.08.2024

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