Tripathi Heart Rate and Rhythm

Heart Rate and Rhythm

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Molecular Basis, Pharmacological Modulation and Clinical Implications

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Beschreibung

This completely updated and expanded 2nd Edition provides all the information needed in order to understand the complex molecular, cellular and genetic mechanisms that underlie normal and abnormal cardiac rhythms. Its goal is to help physiologists and clinicians alike develop better preventive and treatment strategies.

The respective chapters cover a broad range of topics, including the role of specific ion channels and transporters, gap junctions, intracellular Ca2+ handling in pacemaker activity, impulse conduction, and the activity of atrial and ventricular myocardium. Special emphasis is placed on the unique electrophysiology of specialized pacemaking cells and conducting fibers. In turn, several types of inherited and acquired ventricular arrhythmias are presented in detail. Clinicians will especially appreciate the updated information on even common disorders like atrial fibrillation and their impacts on human physiology.

In closing, the book goes “one step further” and considers future prospects, e.g. novel antiarrhythmic agents and new concepts like optogenetics, in the context of heart rate regulation. Accordingly, it offers readers a solid reference guide to everything they need to know about human heart rate and rhythm.


This completely updated and expanded 2nd Edition provides all the information needed in order to understand the complex molecular, cellular and genetic mechanisms that underlie normal and abnormal cardiac rhythms. Its goal is to help physiologists and clinicians alike develop better preventive and treatment strategies.

The respective chapters cover a broad range of topics, including the role of specific ion channels and transporters, gap junctions, intracellular Ca2+ handling in pacemaker activity, impulse conduction, and the activity of atrial and ventricular myocardium. Special emphasis is placed on the unique electrophysiology of specialized pacemaking cells and conducting fibers. In turn, several types of inherited and acquired ventricular arrhythmias are presented in detail. Clinicians will especially appreciate the updated information on even common disorders like atrial fibrillation and their impacts on human physiology.

In closing, the book goes “one step further” and considers future prospects, e.g. novel antiarrhythmic agents and new concepts like optogenetics, in the context of heart rate regulation. Accordingly, it offers readers a solid reference guide to everything they need to know about human heart rate and rhythm.


Examines molecular and cellular mechanisms underlying normal and pathological cardiac rhythm Explores optogenetics in relation to arrhythmia and its treatment Broadens understanding of neurocardiology and arrhythmias

Autor*in

Onkar N. Tripathi

Themen in »Heart Rate and Rhythm«

Arrhythmogenesis Atrial Fibrillation Atrioventricular Junction Brugada Syndrome Cardiac Pacemaker CPVT Intracellular Ca Myocard Purkinje Fibres SA Node

Stimmen zu »Heart Rate and Rhythm«

Details

ISBN: 9783031335907
Verlag: Springer International Publishing
Erscheinung: 08.12.2024

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