Advances in Maternal-Fetal Biomedicine
Cellular and Molecular Mechanisms of Pregnancy Pathologies
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Beschreibung
This textbook aims to describe physiological and pathophysiological mechanisms that underlie human maternal-fetal interactions. The book emphasizes the structure and development of the fetoplacental unit, the endocrine and nutritional regulation of fetal development, nitric oxide signalling, solute carriers function and ion channels regulation in healthy pregnancies and diseases, like preeclampsia, gestational diabetes, and maternal obesity, among others. Also, we highlight novel mechanisms associated with language impairment in children, the use of serotonin inhibitors or cannabis during pregnancy, and maternal conditions' potential impact on cerebrovascular development in newborns and infants. The cellular and molecular understanding of maternal-fetal physiology and pathophysiology will allow the readers to understand the impact of diseases or conditions that are highly prevalent in pregnant women.
This edited volumeaims to describe physiological and pathophysiological mechanisms that underlie human maternal-fetal interactions. The book emphasizes the structure and development of the fetoplacental unit, the endocrine and nutritional regulation of fetal development, nitric oxide signalling, solute carriers function and ion channels regulation in healthy pregnancies and diseases, like preeclampsia, gestational diabetes, and maternal obesity, among others. Also, we highlight novel mechanisms associated with language impairment in children, the use of serotonin inhibitors or cannabis during pregnancy, and maternal conditions' potential impact on cerebrovascular development in newborns and infants. The cellular and molecular understanding of maternal-fetal physiology and pathophysiology will allow the readers to understand the impact of diseases or conditions that are highly prevalent in pregnant women.
Contains molecular descriptions of relevant pathologies of pregnancy Written by a leading group of researchers who are at the frontier of knowledge in maternal-fetal biomedicine Offers an integrative view that includes clinical information and translational medicine approaches
Autor*in
Marcelo Gonzalez-Ortiz
Themen in »Advances in Maternal-Fetal Biomedicine«
Placenta Trophoblast Fetal endothelium Preeclampsia Gestational diabetes Fetal programming Gestational weight gain Perinatal outcomes Fetal restriction Macrosomia Nitric oxide Placental transport Exosomes