A Scientific Approach to Improving Animal Research in Biomedicine

Beschreibung

This book examines animal research conducted with the goal of medical translation to humans. It is written by Dr. Bradley Weiner, a surgeon who is active at a high level clinically and in biomedical research. After documenting that the vast majority of biomedical animal research fails to result in benefits to humans via translation, the book examines the sources of such failure; including the failure to justify the use of animals, the failure to properly apply scientific methods, the failure to perform the research properly in the lab, the failure to consider the possibility of translation a priori, and systematic sources of failure built into the biomedical research enterprise. The book then explores options to improve the situation, for the benefit of both the animals and humans.
This book examines animal research conducted with the goal of medical translation to humans. It is written by Dr. Bradley Weiner, a surgeon who is active at a high level clinically and in biomedical research. After documenting that the vast majority of biomedical animal research fails to result in benefits to humans via translation, the book examines the sources of such failure; including the failure to justify the use of animals, the failure to properly apply scientific methods, the failure to perform the research properly in the lab, the failure to consider the possibility of translation a priori, and systematic sources of failure built into the biomedical research enterprise. The book then explores options to improve the situation, for the benefit of both the animals and humans.
Provides insight into failures of scientific methodology in medical and animal research Covers the failures of scientific methodologies used in animal research with multiple practical examples Provides a clear outline for setting up the ideal study to ensure animals used for animal

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Bradley K. Weiner

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medical research animal research scientific methods scientific ethics medical ethics medical philosophy

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