Golgi pH and Ion Homeostasis in Health and Disease
Elham Khosrowabadi and Sakari KellokumpuLipid Droplets in Cancer
Toni PetanPatterns of Ciliation and Ciliary Signaling in Cancer
Anna A. Kiseleva, Anna S. Nikonova, and Erica A. GolemisTargeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs
Anne-Marie Ellegaard, Peter Bach, and Marja JäätteläCancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs)
Alberto Danese, Saverio Marchi, Veronica Angela Maria Vitto, Lorenzo Modesti, Sara Leo, Mariusz R. Wieckowski, Carlotta Giorgi, and Paolo PintonEndosomal Acid-Base Homeostasis in Neurodegenerative Diseases
Hari Prasad and RajiniRaoThis book sheds light on how dysregulated organelle functions contribute to the pathology and progression of human diseases. To offer a broad perspective, they discuss basic, translational, and clinical aspects across scales, from molecules to cells, tissues and organisms. Rather than providing a comprehensive introduction to the field, the authors focus on recent advances in organelle research, with each chapter inviting readers to consider today’s key questions in the respective field.
This book reviews the endoplasmic reticulum, Golgi Appartus, Lysosomes and other membrane-enclosed organelles, demonstrating how their dysregulated function contributes to various pathologies. The chapters not only offer a platform for new perspectives but also stimulate further investigations.
Given the translational nature of this subject, this book is a valuable resource for physiologists and clinicians alike.
Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Stine Helene Falsig Pedersen
homeostasis translational research Lipid Droplets Primary Cilia inflammation redox balance stress granules