Pedersen Organelles in Disease

Organelles in Disease

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Beschreibung

Golgi pH and Ion Homeostasis in Health and Disease 

Elham Khosrowabadi and Sakari Kellokumpu
Stress Granules in Cancer 
Min-Seok Song and Elda Grabocka

Lipid Droplets in Cancer

Toni Petan

Patterns of Ciliation and Ciliary Signaling in Cancer

Anna A. Kiseleva, Anna S. Nikonova, and Erica A. Golemis

Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs 

Anne-Marie Ellegaard, Peter Bach, and Marja Jäättelä

Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs) 

Alberto Danese, Saverio Marchi, Veronica Angela Maria Vitto, Lorenzo Modesti, Sara Leo, Mariusz R. Wieckowski, Carlotta Giorgi, and Paolo Pinton

Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases 

Hari Prasad and RajiniRao
Endolysosomal Disorders Affecting the Proximal Tubule of the Kidney: New Mechanistic Insights and TherapeuticsBeatrice Paola Festa, Marine Berquez, Daniela Nieri, and Alessandro Luciani
Endo-Lysosomal Cation Channels and Infectious Diseases Yu-Kai Chao, Sui-Yuan Chang, and Christian Grimm
Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book sheds light on how dysregulated organelle functions contribute to the pathology and progression of human diseases. To offer a broad perspective, they discuss basic, translational, and clinical aspects across scales, from molecules to cells, tissues and organisms. Rather than providing a comprehensive introduction to the field, the authors focus on recent advances in organelle research, with each chapter inviting readers to consider today’s key questions in the respective field.

This book reviews the endoplasmic reticulum, Golgi Appartus, Lysosomes and other membrane-enclosed organelles, demonstrating how their dysregulated function contributes to various pathologies. The chapters not only offer a platform for new perspectives but also stimulate further investigations.

Given the translational nature of this subject, this book is a valuable resource for physiologists and clinicians alike.

Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.


Connects basic cell biology with medical application opportunities Provides insights from both laboratory and clinical research Contributes to a progessive scientific discussion in molecular medicine

Autor*in

Stine Helene Falsig Pedersen

Themen in »Organelles in Disease«

homeostasis translational research Lipid Droplets Primary Cilia inflammation redox balance stress granules

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Details

ISBN: 9783031225949
Verlag: Springer International Publishing
Erscheinung: 28.01.2023

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