Systems Biology of MicroRNAs in Cancer
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Beschreibung
This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research.
Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance.
Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research.
Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance.
Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
Provides up-to-date information on cancer-related microRNA research, with focus on computational data analysis Focuses on the use of microRNAs in cancer diagnosis and treatment Includes contributions from internationally renowned clinicians and bioinformaticians from around the globe
Autor*in
Ulf Schmitz
Themen in »Systems Biology of MicroRNAs in Cancer«
Bioinformatics Cancer Cancer Regulation Gene Regulation Immunotherapy Immune Cells MicroRNA MicroRNA-target Prediction Next Generation Sequencing Non-coding RNA p53 Systems Biology