Transportome Malfunction in the Cancer Spectrum
Ion Transport in Tumor Biology
Buch in deiner Nähe kaufen
Beschreibung
Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression
Halima Ouadid-Ahidouch, Hamid Morjani, Julie Schnipper, Alban Girault, and Ahmed Ahidouch
Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening
Valerio Farfariello, Natalia Prevarskaya, and Dimitra Gkika
Ion Channels in Lung Cancer
Etmar Bulk, Luca Matteo Todesca, and Albrecht Schwab
Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer
Giuliano Ciarimboli, Gerit Theil, Joanna Bialek, and Bayram Edemir
Transportome Malfunctions and the Hallmarks of Pancreatic Cancer
Qi Ling and Holger Kalthoff
How Dysregulated Ion Channels and Transporters Take a Hand in Esophageal, Liver, and Colorectal Cancer
Christian Stock
Ion Channels in Glioma Malignancy
Luigi Catacuzzeno, Luigi Sforna, Vincenzo Esposito, Cristina Limatola, and Fabio Franciolini
Membrane Transporters and Channels in Melanoma
Ines Böhme, Roland Schönherr, Jürgen Eberle, and Anja Katrin Bosserhoff
Ion Channel Dysregulation in Head and Neck Cancers: Perspectives for Clinical Application
Nagore Del-Río-Ibisate, Rocío Granda-Díaz, Juan P. Rodrigo, Sofía T. Menéndez, and Juana M. García-Pedrero
This is the first of three volumes in the "Ion Channels & Transporters in Tumor Biology" collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis. The authors highlight the role of the so-called transportome, which is defined by the entirety of ion transporters and ion channels. Thereby, readers will get a better understanding of the impact dysregulated ion transport has on the whole spectrum of cancer types. Cancers display deficiencies in several, sometimes interdependent members of the transportome.
Clinicians will be interested in the fact that controlled expression of ion transport proteins dramatically impacts the life span of cancer patients, as shown in recent studies. These observations offer a promising outlook for biomedical scientists, as members of the transportome could be the tumor markers of tomorrow - both for diagnostic and therapeutic purposes.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians from the cancer field.
Highlights the correlation between tumor malignancy and ion channel function and expression Provides examples of how malfunctioning ion transport proteins promote cancer initiation and progression Enriches the understanding of designing therapeutic approaches directed at the transportome
Autor*in
Christian Stock
Themen in »Transportome Malfunction in the Cancer Spectrum«
Kaplan-Meier-Plot malignancy metastasis aggressive cancer ion channels