Inflammation and Epilepsy: New Vistas
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Beschreibung
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
First comprehensive volume discussing epilepsy as an inflammatory disease Projected towards the future, not a review of the past Of interest to both neurologists and neuroscientists
Autor*in
Damir Janigro
Themen in »Inflammation and Epilepsy: New Vistas«
Brain-body Axis Cerebrovasculature Epilepsy Inflammatory Mechanisms Microbiota Maternal and Perinatal Influences Neurological Diseases Therapeutic Targets infectious diseases