Romas Baronas Feliksas Ivanauskas Juozas Kulys Baronas Mathematical Modeling of Biosensors

Mathematical Modeling of Biosensors

von Romas Baronas Feliksas Ivanauskas Juozas Kulys

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Beschreibung

This newly designed and enlarged edition offers an up-to-date presentation of biosensor development and modeling from both a chemical and a mathematical point of view. An entire new chapter in particular is dedicated to optimal design of biosensors. Two more new chapters discuss biosensors which utilize microbial cells and are based on carbon nanotubes respectively. All the other chapters have been revised and updated. 

The book contains unique modeling methods for amperometric, potentiometric and optical  biosensors based mainly on biocatalysts . It examines processes that occur in the sensors' layers and at their interface, and it provides analytical and numerical methods to solve equations of conjugated enzymatic (chemical) and diffusion processes. The action of single enzyme as well as polyenzyme biosensors and biosensors based on chemically modified electrodes is studied. The modeling of biosensors that contain perforated membranes and multipart mass transport profiles is critically investigated. Furthermore, it is fully described how signals can be biochemically amplified, how cascades of enzymatic substrate conversion are triggered, and how signals are processed via a chemometric approach and artificial neuronal networks. The results of digital modeling are compared with both proximal analytical solutions and experimental data.

 



This newly designed and enlarged edition offers an up-to-date presentation of biosensor development and modeling from both a chemical and a mathematical point of view. An entire new chapter in particular is dedicated to optimal design of biosensors. Two more new chapters discuss biosensors which utilize microbial cells and are based on carbon nanotubes respectively. All the other chapters have been revised and updated. 

 The book contains unique modeling methods for amperometric, potentiometric and optical  biosensors based mainly on biocatalysts . It examines processes that occur in the sensors' layers and at their interface, and it provides analytical and numerical methods to solve equations of conjugated enzymatic (chemical) and diffusion processes. The action of single enzyme as well as polyenzyme biosensors and biosensors based on chemically modified electrodes is studied. The modeling of biosensors that contain perforated membranes and multipart mass transport profiles is critically investigated. Furthermore, it is fully described how signals can be biochemically amplified, how cascades of enzymatic substrate conversion are triggered, and how signals are processed via a chemometric approach and artificial neuronal networks. The results of digital modeling are compared with both proximal analytical solutions and experimental data.

 



Great compendium of biosensor development and their mathematical modeling Presents unique modeling methods for a wide range of biosensors Builds on success of earlier edition, offering new insights on optimal design of biosensors

Autor*in

Romas Baronas

Themen in »Mathematical Modeling of Biosensors«

carbon nanotube based biosensors optimal design of biosensors Enzymatic Kinetic Nernst diffusion layer bi-enzyme biosensors microbial cells consecutive substrates conversion parallel substrates conversion cyclic substrates conversion synergistic substrates conversion glucose dehydrogenase-based biosensor chemically modified electrodes perforated membranes Non Michaelis–Menten Enzyme heterogeneous microreactor

Stimmen zu »Mathematical Modeling of Biosensors«

Details

ISBN: 9783030655075
Verlag: Springer International Publishing
Erscheinung: 17.02.2022

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