Schreiber Modern CNS Drug Discovery

Modern CNS Drug Discovery

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Reinventing the Treatment of Psychiatric and Neurological Disorders

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Beschreibung

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug.

Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs.

Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.


This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug.

Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs.

Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.


Watch a fantastic video to the book here: https://www.youtube.com/watch?v=uJFO38zYXOk&t=42s Provides unique perspectives from scientists in both academia and industry on how a new model for discovering drugs for brain disorders is currently emerging Presents a comprehensive overview of the currently used technologies, approaches and concepts in drug discovery for a full spectrum of disorders of the central nervous system

Autor*in

Rudy Schreiber

Themen in »Modern CNS Drug Discovery«

drug development drug screening Neurological Disorders pharmaceutical industry drug development pipeline Biomarkers clinical trials Drug Discovery Brain Imaging Clinical Development Central Nervous System Neuroinformatics Novel Therapeutics Psychopharmacology Psychiatric Disorders

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Details

ISBN: 9783030623531
Verlag: Springer International Publishing
Erscheinung: 18.06.2022

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