Neurodevelopmental Disorders
Employing iPSC Technologies to Define and Treat Childhood Brain Diseases
Buch in deiner Nähe kaufen
Beschreibung
This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.
This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular andmolecular phenotypes.
Provides a compendium of iPSC reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders Discusses common phenotypes and potential molecular mechanisms among diverse neurodevelopmental disorders Suitable for basic and clinical neuroscientists, clinicians, psychologists, other health related practitioners and educators
Autor*in
Emanuel DiCicco-Bloom
Themen in »Neurodevelopmental Disorders«
iPSCs Autism Schizophrenia Syndromic Autism Bipolar Disorder Neurodevelopmental Gene Risk Factors