Peter F. Thall Thall Statistical Remedies for Medical Researchers

Statistical Remedies for Medical Researchers

von Peter F. Thall

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Beschreibung

This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious.  For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect inferences being made. The technical level is kept to a minimum to make the book accessible to non-statisticians. At the same time, since many of the examples describe methods used routinely by medical statisticians with formal statistical training, the book appeals to a broad readership in the medical research community.


This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious.  For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect inferences being made. The technical level is kept to a minimum to make the book accessible to non-statisticians. At the same time, since many of the examples describe methods used routinely by medical statisticians with formal statistical training, the book appeals to a broad readership in the medical research community.


Includes examples of a wide variety of common statistical errors and misconceptions in medical data analysis and clinical trial design, with at least one alternative solution for each problem, to provide statistical tools that can be used in practice Written in an informal style with technical content kept to a reasonably low level, making it accessible to non-statisticians as well as statisticians Is the first book of its kind for the medical research community

Autor*in

Peter F. Thall

Themen in »Statistical Remedies for Medical Researchers«

Hypothesis testing Bayesian statistics Survival analysis P-value Clinical trials Adaptive randomization Phase I Trials Confounding Expansion cohorts Bias correction Monitoring toxicity Design of medical experiments Analysis of medical experiments Dose finding Dynamic treatment regimes

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“This is an excellent book ... written primarily for medical researchers and statisticians working in the medical research sector. ... I'd conclude by extending my hearty congratulations to the author for contributing such a wonderful volume to the biostatistics literature.” (Bibhas Chakraborty, International Statistical Review, Vol. 88 (3), 2020)

“This book can be recommended to a statistician that is starting a career in drug development and pharma research, or a statistician in this area willing to receive some food for thought and foster critical thinking.” (ISCB News, iscb.info, Issue 70, December, 2020)



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Details

ISBN: 9783030437169
Verlag: Springer International Publishing
Erscheinung: 13.03.2021

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