Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics
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Beschreibung
This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.
This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.
Nominated as an outstanding PhD thesis by the Australian Institute for Bioengineering and Nanotechnology Describes the design of various novel nano-strategies for prostate cancer detection Offers an extensive investigation into the use of next-generation urinary biomarkers Includes data on clinical evaluation to progress clinical translation
Autor*in
Kevin M. Koo
Themen in »Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics«
Prostate Cancer Detection Precision Medicine Urinary Nanodiagnostics Clinical Translation Biosensor Development Next-generation Prostate Cancer Biomarkers Non-invasive Prostate Cancer Nanodiagnostics TMPRSS2–ETS Fusion Genes Electro Chemistry Surface-enhanced Raman spectroscopy Enhanced Detection Performance Nanodiagnostics for Clinical Applications Lab-in-a-drop Fluidic Mixing