Ton J. Cleophas Aeilko H. Zwinderman Cleophas Efficacy Analysis in Clinical Trials an Update

Efficacy Analysis in Clinical Trials an Update

von Ton J. Cleophas Aeilko H. Zwinderman

Efficacy Analysis in an Era of Machine Learning

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Beschreibung

Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables.

Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required.  

This is the first publication of clinical trials that have been systematically analyzed with machine learning. In addition, all of the machine learning analyses were tested against traditional analyses. Step by step statistics for self-assessments are included.

The authors conclude, that machine learning is often more informative, and provides better sensitivities of testing than traditional analytic methods do.


Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables

Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required

This is the first publication of clinical trials that have been systematically analyzed with machine learning. In addition, all of the machine learning analyses were tested against traditional analyses. Step by step statistics for self-assessments are included

The authors conclude, that machine learning is often more informative, and provides better sensitivities of testing than traditional analytic methods do



It shows, for the first time, that machine learning methodologies can be used for assessing efficacy data of controlled clinical trials It confirms, that machine learning methodologies provide better sensitivity of testing It confirms, that machine learning methodologies are more informative

Autor*in

Ton J. Cleophas

Themen in »Efficacy Analysis in Clinical Trials an Update«

Clinical trials Traditional efficacy analysis Machine learning for efficacy analysis Data mining Big data validation

Stimmen zu »Efficacy Analysis in Clinical Trials an Update«

Details

ISBN: 9783030199180
Verlag: Springer International Publishing
Erscheinung: 03.09.2019

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