Myelodysplastic Syndromes
Diagnosis - Prognosis - Therapy
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Beschreibung
This book reviews the standard diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS) and examines ongoing research developments in the field. The importance of appropriate prognostic stratification, taking into account recent advances in understanding of the molecular pathogenesis of MDS, is explained, and both established and novel treatment approaches are discussed in depth. The coverage includes, for example, the use of erythropoietic stimulating agents, iron chelation therapy, the immunomodulator lenalidomide, hypomethylating agents such as azacitidine, and allogeneic hematopoietic stem cell transplantation.
Myelodysplastic syndromes are heterogeneous and complex hematologic disorders ranging from indolent conditions to forms approaching the aggressiveness of acute myeloid leukemia. The diversity of MDS gives rise to challenges in diagnosis and clinical decision making, and the highly variable clinical course necessitates a risk-adapted treatmentstrategy and the application of disease-specific therapies. Hematologists, oncologists, and other interested clinicians will find this book to be an invaluable source of information on diagnostic and prognostic evaluation and treatment selection.
This book reviews the standard diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS) and examines ongoing research developments in the field. The importance of appropriate prognostic stratification, taking into account recent advances in understanding of the molecular pathogenesis of MDS, is explained, and both established and novel treatment approaches are discussed in depth. The coverage includes, for example, the use of erythropoietic stimulating agents, iron chelation therapy, the immunomodulator lenalidomide, hypomethylating agents such as azacitidine, and allogeneic hematopoietic stem cell transplantation.
Myelodysplastic syndromes are heterogeneous and complex hematologic disorders ranging from indolent conditions to forms approaching the aggressiveness of acute myeloid leukemia. The diversity of MDS gives rise to challenges in diagnosis and clinical decision making, and the highly variable clinical course necessitates a risk-adapted treatment strategy and the application of disease-specific therapies. Hematologists, oncologists, and other interested clinicians will find this book to be an invaluable source of information on diagnostic and prognostic evaluation and treatment selection.
Provides a comprehensive overview on all clinical aspects of myelodysplastic syndromes Presents novel therapeutic approaches Written by distinguished experts
Autor*in
Uwe Platzbecker
Themen in »Myelodysplastic Syndromes«
Myelodysplastic Syndromes Anemia Erythropoietic Stimulating Agents Hypomethylating Agents Iron Chelation Therapy
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“This is an up‐to‐date review of the diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS). In light of the recent advances in this field, the book makes a laudable effort to highlight the importance of prognostic stratification and discusses in depth both standard therapeutic practices and novel approaches. … At barely 150 pages, this comprehensive yet succinct book is an excellent resource on MDS that is very informative, authoritative, and easy to read.” (Ravi Salgia, Doody's Book Reviews, December 14, 2018)
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