Cell-Based Therapy for Degenerative Retinal Disease
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Beschreibung
This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
Explores why specific diseases are targeted for cell-based retinal therapy, including evidence that justifies optimism for the approach Discusses the challenges that must be managed in order to transition the technology from the laboratory into routine clinical practice Argues that “de-risking” can be achieved with preclinical experimentation in advance of human trials
Autor*in
Marco A. Zarbin
Themen in »Cell-Based Therapy for Degenerative Retinal Disease«
retinal pigment epithelium cns cell therapy stem cells reprogramming cells neural progenitor cells