In this new volume, renowned authors contribute fascinating, cutting-edge insights into microarray data analysis. Information on an array of topics is included in this innovative book including in-depth insights into presentations of genomic signal processing. Also detailed is the use of tiling arrays for large genomes analysis. The protocols follow the successful Methods in Molecular Biology™ series format, offering step-by-step instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting. This book will help the reader master the tricks of the trade and avoid pitfalls.
Information on an array of topics including genomic signal processing, matrix algebra and genetic networks, predictive models of gene regulation, comparing microarray studies, identifying progression-associated genes in astrocytoma, analysis of comparative genomic hybridization data on cDNA microarrays, statistical framework for gene expression analysis, and interpretation ingof microarray results with gene ontology and MeSH ontology Use classic, novel, and state-of-the-art methods in a readily reproducible format Master tricks of the trade, troubleshoot, and avoid known pitfalls