Developmental Toxicology
Methods and Protocols
Buch in deiner Nähe kaufen
Beschreibung
This thorough edition explores numerous methodological approaches that can be extremely informative for our understanding of the developmental toxicant mechanisms, characterization of developmental outcomes, and development of potential interventions that are clinically relevant. Presenting both staple and state-of-the-art approaches, the book focuses on numerous cellular models (induced pluripotent stem cells, neural crest culture, etc.), some less frequently used but important animal models (chick, zebrafish), in vitro approaches using whole embryos (rat, mouse and rabbit), and specific outcome methodologies to assess changes on the morphological to molecular level. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that allows for smooth processes in the lab.
Authoritative and practical, Developmental Toxicology: Methods and Protocols, Second Editionserves as an ideal aid to support further investigation into the specific mechanisms and outcomes of developmental exposures.
This thorough edition explores numerous methodological approaches that can be extremely informative for our understanding of the developmental toxicant mechanisms, characterization of developmental outcomes, and development of potential interventions that are clinically relevant. Presenting both staple and state-of-the-art approaches, the book focuses on numerous cellular models (induced pluripotent stem cells, neural crest culture, etc.), some less frequently used but important animal models (chick, zebrafish), in vitro approaches using whole embryos (rat, mouse and rabbit), and specific outcome methodologies to assess changes on the morphological to molecular level. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that allows for smooth processes in the lab.
Authoritative and practical, Developmental Toxicology: Methods and Protocols, Second Editionserves as an ideal aid to support further investigation into the specific mechanisms and outcomes of developmental exposures.
Includes cutting-edge, fully updated techniques Provides step-by-step detail essential for reproducible results Contains key implementation advice from the experts
Autor*in
Jason M. Hansen
Themen in »Developmental Toxicology«
In utero exposures Fetal basis of disease Toxicant mechanisms Toxicity Embryology Prenatal exposure Cellular models Animal models