Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma
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Beschreibung
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
Reviews major advances in molecular methods, using an evidence-based perspective Explores powerful tools for determining treatment decisions An essential resource for oncologists, dermatologists, pathologists, and melanoma researchers Includes supplementary material: sn.pub/extras
Autor*in
Michael J. Murphy
Themen in »Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma«
Epigenetic Biomarkers Lymph Node Disease Serological Disease microRNA Biomarkers
Stimmen zu »Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma«
From the reviews:
“This is a comprehensive overview of biomarkers as they relate to pathogenesis and clinical utility in the diagnosis, staging, and treatment of melanoma. … The audience is practitioners specializing in melanoma, including dermatologists, surgeons, and oncologists, as well as researchers in the field. … book broadly explores the role of molecular diagnostic techniques and specific biomarkers which may serve to facilitate more accurate diagnoses and identify early-stage melanoma patients with high risk for metastasis. … I highly recommend this book for melanoma clinicians and researchers.” (Susan M. Swetter, Doody’s Book Reviews, July, 2012)()