The first book to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries. White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event.
Selva Baltan
encephalopathy neurodegeneration stroke white matter
From the reviews:
“This is an excellent text concerning white matter and the ischemic penumbra of focal cerebral ischemia. This is a very recent review of the literature about inflammatory mediators of injury such as the interleukins, prostaglandins, granulocyte chemotactic factor, and biochemical signal transduction agents. It ties all this information concerning the pathophysiology with autophagocytosis involving membrane proteins, like the chaperones molecules, and lysosomes. I would recommend this book for neurologists, neurosurgeons, students, ischemia researchers, and physiologists.” (Joseph J. Grenier, Amazon.com, May, 2014)