DNA Tumor Viruses
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Beschreibung
The DNA tumor viruses are central to many branches of molecular and cellular biology. This very diverse group of viruses attack common cellular pathways, which makes them powerful tools for understanding how multiple complex pathways are integrated. Additionally, the unique mechanisms employed by each viral system to alter cellular functions serve as powerful molecular probes for the identification of new targets and pathways. The scientific impact of the DNA tumor viruses extends far beyond their etiologic role in human cancers, or their contributions to our basic understanding of the cellular pathways that drive tumorigenesis. Currently, research on these viruses lies at the interface of cancer and the innate and adaptive immune response, investigating how infectious agents influence, evade, and utilize systems that regulate these processes. Thus, DNA tumor viruses serve as models for the systems biology of host-pathogen interactions.
"DNA Tumor Viruses," edited by Blossom Damania and James M. Pipas, summarizes recent advances in our understanding of this diverse and fascinating collection of viruses.
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. The main textbook in this market, Fields, which is referred to by both reviewers, covers some of these topics but on a lower level. The only two books that are nearly as comprehensive as this one are Human Tumor Viruses, which was published by the American Society for Microbiology in 1998 and is quite outdated, and Viruses, Cell Transformation, and Cancer, which was published by Elsevier in 2001. This book is the first current, comprehensive review of its kind in the market.
DNA Tumor Viruses will focus on the DNA viruses in the human population that are associated with cancers. It will cover most of the viruses that are thought to contribute to human malignancy. Additionally, our author team is very strong—Blossom Damania is a Leukemia & Lymphoma Society Scholar, a V Foundation for Cancer Research Scholar, a Burroughs Wellcome Investigator in Infectious Disease, and the 2004 recipient of the AACR-Gertrude Elion Scholar award. Jim Pipas is internationally renowned in the field of SV40 research and an NIH Merit award recipient. Represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that will be also covered in this book, there is no single book that covers this topic comprehensively
Autor*in
Blossom Damania
Themen in »DNA Tumor Viruses«
AIDS DNA DNA tumor viruses Epstein-Barr Virus HPV strains KSHV MHV68 Polyomaviruses Virus genes infection miRNAs papillomavirus vaccines infectious diseases