Microdroplet Technology
Principles and Emerging Applications in Biology and Chemistry
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Beschreibung
Over the last 20 years of microfluidics and chip engineering, so-called “Lab on Chip” technology has led to many exciting results, PhD theses, books, journal publications, several new journals, and commercial products. Trends have shifted from applications in chemistry to cell biology and clinical diagnostics, from electrophoresis and biosensors to digital microfluidics and droplet-based methods, and from micrometre-sized features to nanostructures and molecular self-assembly.
And there seem to be no limits in sight. The only problem arising is that academic research continues to proceed at an ever increasing pace compared to the real-world applications and commercialisation of “Lab on Chip”. Therefore, the purpose of this book is to bring together authors in this multidisciplinary field to provide overviewsof two-phase flow, droplets, and digital microfluidics for biological and medical applications. It is currently the only book dedicated to droplets in microfluidics that goes beyond electrowetting methods. Included are the novel areas of next generation sequencing and emulsion PCR (polymerase chain reaction), together with analyses on the ramifications of droplet-based reactions for biochemical assays and their commercial viability.
Microdroplet technology has recently emerged to provide new and diverse applications via microfluidic functionality, especially in various areas of biology and chemistry. This book, then, gives an overview of the principle components and wide-ranging applications for state-of-the-art of droplet-based microfluidics. Chapter authors are internationally-leading researchers from chemistry, biology, physics and engineering that present various key aspects of micrdroplet technology -- fundamental flow physics, methodology and components for flow control, applications in biology and chemistry, and a discussion of future perspectives. This book acts as a reference for academics, post-graduate students, and researcher wishing to deepen their understand of microfluidics and introduce optimal design and operation of new droplet-based microfluidic devices for more comprehensive analyte assessments.
The only book dedicated to microdroplets in microfluidics to go beyond electrowetting Includes the novel areas of next generation sequencing and emulsion PCR Analyzes the ramifications of dropletized reactions for biochemical analytical essays Includes supplementary material: sn.pub/extras
Autor*in
Philip Day
Themen in »Microdroplet Technology«
DNA diagnostics Flow control digital microfluidics electrowetting microdroplet microfluidic micropumps microvalves multiphase microflows single-cell