Microarray Gene Expression Data Analysis

Beschreibung

This guide covers aspects of designing microarray experiments andanalysing the data generated, including information on some of thetools that are available from non-commercial sources. Concepts andprinciples underpinning gene expression analysis are emphasised andwherever possible, the mathematics has been simplified. The guideis intended for use by graduates and researchers in bioinformaticsand the life sciences and is also suitable for statisticians whoare interested in the approaches currently used to study geneexpression. * Microarrays are an automated way of carrying out thousands ofexperiments at once, and allows scientists to obtain huge amountsof information very quickly * Short, concise text on this difficult topic area * Clear illustrations throughout * Written by well-known teachers in the subject * Provides insight into how to analyse the data produced frommicroarrays

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Helen Causton

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Biowissenschaften Cell & Molecular Biology Life Sciences Zell- u. Molekularbiologie

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"Quite a few recently published books discuss analysis ofmicroarray gene expression data for beginners. Microarray GeneExpression Data Analysis ... is arguably the best of its kindin this regard." Terry Speed, The Walter & Eliza HallInstitute of Medical Research, Nature Cell Biology, December2003 "Overall this is an excellent book, it is well referenced and,to my mind, covers the vast majority of issues an experimenterneeds to consider when venturing into the world of microarray dataanalysis. The book fills a clear gap in the field, providing arigorous overview of the often confusing .... data analysis issuesthat most books on microarrays avoid or treat in a cursory way. Iwould say it is essential reading for any laboratory or researcheractive in this rapidly evolving field and is recommended for themathematician or statisitican who is interested in the field or whohas been persuaded by their biologist colleague to help them withtheir analysis." Steven Russell, University of Cambridge,Genetical Research, February 2003 "Anyone wishing to gain a basic understanding of microarray geneexpression studies will come away enriched ... A good andaccessible entry point for any biologist who is interested ingetting an overview about how to perform microarray gene expressionstudies." D.C.Jamison, George Mason University, Heredity, June2004
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