Pharmaco-Complexity
Non-Linear Phenomena and Drug Product Development
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Beschreibung
The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena.
The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena.
Describes topics that indicate a need for a non-linear interpretation if they are to be characterized accurately, understood fully and potentially controlled or modulated in the service of improved therapeutic strategies Promotes discussion of phenomena leading to pharmacological effect and the complex interactions ultimately resulting in improved disease control and health maintenance Includes supplementary material: sn.pub/extras
Autor*in
Anthony J. Hickey
Themen in »Pharmaco-Complexity«
Complexity Development Drug Hickey Pharmaco Phenomena Product Smyth