Steroid Analysis

Beschreibung

This comprehensive and up-to-date 2nd edition of the Steroid Analysis handbook, written by a team of distinguished experts from around the world concentrates on the analysis of steroids in biological fluids. This edition is based on the same format as the first, primarily dealing with analysis of low levels of steroid analytes in biological fluids, but including an extra chapter on pharmaceutical aspects of steroid analysis. Spectroscopic and other methods, including UV and IR absorption spectroscopy, NMR spectroscopy, mass spectrometry, X-ray diffraction, chromatography and immunoassay of steroids are treated in detail. Discussion of general methods for extraction, purification and quantitation is followed by consideration of the analysis of specific important steroid groups, such as progestagens, estrogens, corticosteroids, vitamins D, bile acids and anabolic steroids and their metabolites. The editors have made a conscious decision to leave the first edition to stand on its own with regards to steroid analysis prior to 1995 and authors therefore were asked to review the modern post-1995 steroid scene, though pre-1995 data were not excluded if authors felt it was necessary. This book should be of interest to analytical chemists, biochemists and chemical pathologists with an interest or involvement in steroids.
The second edition of this book has drawn heavily on the first edition but a huge amount of research on steroid analysis has been published over the last 15 years. As a result, the Editors decided to let the first edition of this book stand on its own and direct readers interested in pre-1995 steroid analysis to it, simply because the post-1995 research can on its own fill the second edition. We have tried to keep a balance but equally have allowed authors of each chapter a significant degree of freedom to approach their particular topics as they thought fit – they are after all the experts in their field. We hope that readers will agree that we have got the balance right. In re-writing or updating these chapters, we have been greatly assisted by the developments in the availability of research publications electronically. Huge strides have been made in this area since 1995 and the ability to read a paper on one’s computer rather than trekking to the British Library is a tremendous advantage. The editors wish to express their gratitude to their respective insti- tions (St. Bartholomew’s and the Royal London School of Medicine, Queen Mary University of London and Kings College London) for providing us with el- tronic access to research journals from our home computers. Without such access, it would have been impossible to complete this book.
Second edition of successful reference on steroid analysis Includes a completely new chapter on pharmaceutical aspects of steroid analysis Comprehensive and up-to-date review of steroid analysis, written by experts in the field Strong focus on developments in steroid analysis since 1995 Includes supplementary material: sn.pub/extras

Autor*in

Hugh L. J. Makin

Themen in »Steroid Analysis«

analysis of androgens analysis of bile acids analysis of corticosteroids analysis of estrogens analysis of progestagens analysis of vitamin D analytes in complex matrices biological fluids detection of anabolic steroids in sport doping and detect

Stimmen zu »Steroid Analysis«

From the reviews of the second edition:

This is an excellent, comprehensive book and can be highly recommended to those who want an up-to-date reference on steroid analysis

“A comprehensive compendium of the broad and complex topics of characterizing and measuring steroidal compounds. … The book is composed of 13 chapters written by 26 experts. … Comprehensiveness and timeliness are particularly unique features of this book. … an interesting and highly recommended read. … a unique book has been produced covering analytical aspects of steroid biochemistry, detection , and quantification in their entire breadth. The clear and balanced content is a well structured source of information for students and researchers in steroid analysis.” (Mario Thevis, Analytical Bioanalytical Chemistry, Vol. 401, 2011)

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