Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

Beschreibung

Many small molecules occur naturally as "messenger" chemicals whichregulate the behaviour and functions of microbes, plants, insectsand animals. Examples include hormones, pheromones, phytoalexins,and antifeedants. These biofunctional molecules are of greatinterest to researchers in helping develop our understanding ofbiological function and in the development of new drugs. Howeverextracting them from nature can be prohibitively expensive, sothere is great interest in devising methods of synthesising themfrom simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and OtherBioregulators is an introduction to the techniques andstrategies for the synthesis of biofunctional small molecules.Topics include: * what are biofunctional molecules? * why must biofunctional molecules be synthesized? * how can we synthesize biofunctional molecules? * the synthesis of phytohormones, phytoalexins and otherbiofunctional molecules of plant origin * the synthesis of insect juvenile hormones and antifeedants * the synthesis of pheromones and the significance of chiralityin pheromone science * the synthesis of microbial hormones and pheromones,antibiotics, and other biofunctional molecules of microbialorigin * the synthesis of marine antifeedants and medicinalcandidates * a synthetic examination of incorrectly proposed structures ofbiomolecules * reflections on science as a human endeavor Drawing on a career of almost 50 years researching and teachingthis subject, Kenji Mori's Chemical Synthesis of Hormones,Pheromones and Other Bioregulators is a must-have textbook forstudents and researchers of organic synthesis and natural products,and a stimulating and inspiring account of a distinguished chemicalcareer.

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Kenji Mori

Themen in »Chemical Synthesis of Hormones, Pheromones and Other Bioregulators«

Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Chemie Chemistry Drug Discovery & Development Natural Products Naturstoffchemie Organic Chemistry Organische Chemie Organische Synthese Wirkstoffforschung u. -entwicklung

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"This volume will reward the attention of anyone interested inorganic synthesis, in natural products chemistry, or in chemicalecology. It should inspire more synthetic organic chemists to payattention to current research on the roles played by smallmolecules in the lives of organisms, and it should encouragebiologists and structural chemists to identify, contact, andcollaborate with chemical colleagues who are mentally andphysically equipped to carry out stereospecific syntheses ofnature's signal molecules." (Journal of theAmerican Chemical Society, 23 February 2011)
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