Handbook of Statistical Systems Biology
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Beschreibung
Systems Biology is now entering a mature phase in which the keyissues are characterising uncertainty and stochastic effects inmathematical models of biological systems. The area is movingtowards a full statistical analysis and probabilistic reasoningover the inferences that can be made from mathematical models. Thishandbook presents a comprehensive guide to the discipline forpractitioners and educators, in providing a full and detailedtreatment of these important and emerging subjects. Leading expertsin systems biology and statistics have come together to provideinsight in to the major ideas in the field, and in particularmethods of specifying and fitting models, and estimating theunknown parameters.
This book:
* Provides a comprehensive account of inference techniques insystems biology.
* Introduces classical and Bayesian statistical methods forcomplex systems.
* Explores networks and graphical modeling as well as a widerange of statistical models for dynamical systems.
* Discusses various applications for statistical systems biology,such as gene regulation and signal transduction.
* Features statistical data analysis on numerous technologies,including metabolic and transcriptomic technologies.
* Presents an in-depth presentation of reverse engineeringapproaches.
* Provides colour illustrations to explain key concepts.
This handbook will be a key resource for researchers practisingsystems biology, and those requiring a comprehensive overview ofthis important field.
Autor*in
Michael Stumpf
Themen in »Handbook of Statistical Systems Biology«
Biowissenschaften Genetics Genetik Life Sciences Molecular Biology Molekularbiologie Statistical Genetics / Microarray Analysis Statistics Statistik Statistische Genetik / Microarray-Analyse
Stimmen zu »Handbook of Statistical Systems Biology«
"A very remarkable collection of essays. Stronglyrecommended to workers in this area." (InternationalStatistical Review, 1 October 2013)
"I would highly recommend this book as a useful guide forthe students and practitioners of systems biology." (Science Progress, 1 September 2012)
"This handbook will be a key resource for researcherspractising systems biology, and those requiring a comprehensiveoverview of this important field." (Zentralblatt MATH,2012)
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