Predictive ADMET
Integrated Approaches in Drug Discovery and Development
Buch in deiner Nähe kaufen
Beschreibung
This book helps readers integrate in silico, invitro, and in vivo ADMET (absorption,distribution, metabolism, elimination and toxicity) and PK(pharmacokinetics) data with routine testing applications so thatpharmaceutical scientists can diagnose ADMET problems and presentappropriate recommendations to move drug discovery programsforward.
The book introduces the current clinical practice for drugdiscovery and development along with the impact on early riskassessment; consolidates the tools and models to intelligentlyintegrate existing in silico, invitro and in vivo ADMET data; anddemonstrates successful cases and lessons learned from real drugdiscovery and development. In short, it is a book aimed to providea practical road map for drug discovery and development scientiststo generate efficacious and safe drugs for unmet medical needs.
Autor*in
Jianling Wang
Themen in »Predictive ADMET«
Analytical Chemistry Analytische Chemie Chemie Chemistry Drug Discovery & Development Medical Science Medizin Pharmacology & Pharmaceutical Medicine Pharmakologie u. Pharmazeutische Medizin Wirkstoffforschung Wirkstoffforschung u. -entwicklung
Stimmen zu »Predictive ADMET«
"In conclusion, this volume fulfills its promise of being a very useful tool for guidance and diagnosis on ADMET matters, and I would recommend it to any scientist in the field." (ChemMedChem, 1 June 2015)
()