Obesity and Overeating

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With the increasing worldwide incidence of obesity and theresulting increase in metabolic disorders such as diabetes,cardiovascular diseases and some cancers, an understanding of themultitude of factors that contribute to obesity is crucial forresearchers to develop more effective treatments. This collectionof overviews and protocols provides the reader with an introductionto the major features of obesity research, including the interplaybetween energy balance, hormones and neurobiological networks. Anoverview is provided which describes the animal models of obesitymost commonly utilized in research. A standardized laboratoryprotocol for producing diet?]induced obesity (DIO) in both mouseand rat is provided as are protocols that describe how dietformulation can be modified to generate mouse models of humanmetabolic pathologies. Protocols are also provided for testing theeffects of dietary manipulations, caloric restriction and potentialtherapeutics. This e-book -- a curated collection from eLS, WIREs, andCurrent Protocols -- offers a fantastic introduction to thefield of obesity research for students or interdisciplinarycollaborators. Table of Contents: Introduction Energy Balance, Obesity and Type 2 Diabetes eLS M. Daniel Lane Neurobiology of Overeating eLS Eric Stice and Kyle S. Burger Primary Hormones and Receptors Studied in ObesityResearch Obesity Hormones in Health and Disease eLS Emrah Caylak Central Dopaminergic Circuitry Controlling Food Intake andReward: Implications for the Regulation of Obesity WIREs Systems Biology and Medicine Zivjena Vuceti and Teresa M. Reyes Protocols Overview of Animal Models of Obesity Current Protocols in Pharmacology Thomas A. Lutz and Stephen C. Woods Diet-Induced Models of Obesity (DIO) in Rodents Current Protocols in Neuroscience Didier Bagnol, Hussien Al-Shamma, Dominic Behan, Kevin Whelan andAndrew J. Grottick Dietary Manipulation of Mouse Metabolism Current Protocols in Molecular Biology Jerome N. Feige, Marie Lagouge and Johan Auwerx

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Anatomie u. Physiologie Anatomy & Physiology Biowissenschaften Fettleibigkeit Gesundheits- u. Sozialwesen Health & Social Care Life Sciences Medical Science Medizin Metabolism & Biochemistry of Nutrition Obesity Stoffwechsel u. Biochemie der Ernährung

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