Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Beschreibung

Make synthesis more green, efficient, and economical Stereoselective multiple bond-forming transformations (MBFTs), which use one synthetic operation to selectively create at least two chemical bonds, decrease the total number of steps and increase atom economy while maximizing structural complexity and the functional diversity. In consequence, they reduce the amount of waste, money, and negative environmental impact of chemical processes. Combining such an important research topic with green chemistry, this book helps chemists identify sustainable stereoselective MBFTs. Along with the discussion of synthetic procedures, the book features discussion of applications for the synthesis of natural products and drug intermediates. Chapters focus on modern tools for efficient stereoselective synthesis proceeding exclusively with MBFTs - including selected examples of domino, multicomponent, or consecutive sequences. In order to make the book useful for readers, it is organized into five main parts including 15 chapters classified by structures of the final product obtained through the chemical process. Special attention is given to synthetic applications in the fields of total synthesis or in the elaboration of biologically relevant targets. The last chapter is specifically devoted to highlight relevant recent industrial developments of MBFTs. Bringing together otherwise-scattered information about a number of key and efficient chemical reactions, this book: * Helps chemists identify green or sustainable stereoselective multiple bond-forming reactions * Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists * Organizes chapters by molecular structure of final products, making for a handbook-style resource * Discusses applications of the synthesis of natural products and of drug intermediates
Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. * Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development * Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists * Organizes chapters by molecular structure of final products, making for a handbook-style resource * Discusses applications of the synthesis of natural products and of drug intermediates * Brings together otherwise-scattered information about a number of key, efficient chemical reactions

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Jean Rodriguez

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Chemie Chemistry Nachhaltige u. Grüne Chemie Organic Chemistry Organische Chemie Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie Sustainable Chemistry & Green Chemistry

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