Therapeutic Targets
Modulation, Inhibition, and Activation
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Beschreibung
The Latest Applications For Cellmechanism Research in Drug Discovery
Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe.
The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more.
Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.
Autor*in
Luis M. Botana
Themen in »Therapeutic Targets«
Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Chemie Chemistry Clinical Pharmacology & Therapeutics Drug Discovery & Development Klinische Pharmakologie u. Therapie Medical Science Medizin Wirkstoffforschung Wirkstoffforschung u. -entwicklung
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"In summary, there are a number of well-written andconstructed, comprehensive monographs that will be of interest toexperts." (ChemMedChem, 1 March 2013)
"The degree to which an integrated, unified, and visionaryperspective emerges across the book is limited. Nonetheless,individual chapters are likely to be very useful to readers in thatspecific research area. The book certainly offers descriptions ofseveral active target development approaches and application ofsuch approaches in specific biological systems." (Doody's, 1 March 2013)
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