High-Density Lipoproteins

Beschreibung

A complete guide to the role of high-density lipoproteins (HDL)in new and emerging therapies With high-density lipoproteins (HDL) playing an increasing rolein cardiovascular disease prevention, there is a growing need foran in-depth look at HDL and its clinical value. This booksummarizes the current state of knowledge in the field, providingfor the first time a comprehensive, systematic, stylisticallycoherent, and up-to-date review of the composition, structure,heterogeneity, metabolism, epidemiology, genetics, and function ofHDL. Divided into three main parts, High-Density Lipoproteins firstexamines normal HDL particles, then describes defective HDL, andfinally addresses the therapeutic normalization of subnormal levelsand defective biological activities of this lipoprotein class. Thebook highlights the functional properties of HDL, which arerelevant to the pathophysiology of atherosclerosis and thrombosis,and discusses the compositional and metabolic heterogeneity of HDLparticles. Readers will come away with a clear understanding of the role ofHDL in biological processes, the potential value of functional HDLas a therapeutic target, and how current and emerging therapies arepoised to influence the treatment of heart disease in thefuture.

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Anatol Kontush

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Biochemie u. Chemische Biologie Biochemistry (Chemical Biology) Cardiovascular Disease Chemie Chemistry Kardiovaskuläre Erkrankung Kardiovaskuläre Erkrankungen Medical Science Medizin Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie

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"In summary, the need for this book is immense: It is anencyclopedia where everyone working in or near the field canquickly find the fact or reference they need. It is a textbook onecan give to a student on the first day in the lab. It is a novelthat can be read when running out of controversies in your ownfield." (ChemMedChem, 1 April 2013)
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