Copper-Mediated Cross-Coupling Reactions

Beschreibung

Complete, up-to-date collection of available catalytic systems and processes Reviewing the latest advances in copper-catalyzed reactions for the formation of carbon-heteroatom and carbon-carbon bonds, this book enables readers to understand what is currently known and possible in the field, as well as where additional research is still needed. The book's comprehensive coverage offers insights into the underlying mechanisms, preparation procedures, and state-of-the-science strategies for copper-catalyzed reactions. Moreover, readers will find a complete collection of available reactions, catalytic systems and processes, as well as current and pending patents. Starting with the Ullmann and Goldberg cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions describes core applications and key advances in the field. The first two sections are dedicated to the formation of C-heteroatom bonds and C-C bonds. The third section explores applications of copper-catalyzed cross-coupling reactions, including industrial uses, and the development of environmentally friendly reactions. Among the highlights of coverage, readers will discover: * Advances that have revolutionized pharmaceutical, polymer, and materials synthesis * Copper-mediated procedures that have been successfully employed to assemble complex targets * Advantages and limitations of using different catalytic systems and cross-coupling partners * Copper-catalyzed cross-coupling reactions in natural product/bioactive molecule synthesis * New methods for conducting copper-mediated reactions with supported catalysts that enable recyclable and reusable systems The book features contributions from an international team of experts and pioneers in the field. Chapters are based on a thorough review and analysis of the literature as well as the authors' firsthand experience. By setting forth the latest procedures, methods, and applications, Copper-Mediated Cross-Coupling Reactions enables investigators to efficiently synthesize pharmaceuticals, polymers, and materials as well as create a broad array of natural products and molecular structures.
Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.

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Gwilherm Evano

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Catalysis Chemie Chemistry Coordination Chemistry Katalyse Koordinationschemie Methods - Synthesis & Techniques Organische Chemie / Methoden, Synthesen, Verfahren

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"The book is a key resource for copper chemistry and a must-have, for experts and students alike." (Angewandte Chemie, 30 May 2014)
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