Virus-Like Particles
Methods and Protocols
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Beschreibung
This detailed volume explores the design, assembly, and application of virus-like particles (VLPs), versatile scaffolds that mimic the repetitive, high-density display of antigens found in nature, triggering robust immune responses without the safety risks associated with live-attenuated or inactivated viruses. At the intersection of virology, molecular biology, and material science, the book collects VLP applications based on their characteristics as delivery vehicles for chemotherapeutics, RNA vaccines, gene therapy, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Virus-Like Particles: Methods and Protocols serves as an ideal guide for researchers learning to speak the structural language of viruses to build a safer, more precise therapeutic future.
This detailed volume explores the design, assembly, and application of virus-like particles (VLPs), versatile scaffolds that mimic the repetitive, high-density display of antigens found in nature, triggering robust immune responses without the safety risks associated with live-attenuated or inactivated viruses. At the intersection of virology, molecular biology, and material science, the book collects VLP applications based on their characteristics as delivery vehicles for chemotherapeutics, RNA vaccines, gene therapy, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Virus-Like Particles: Methods and Protocols serves as an ideal guide for researchers learning to speak the structural language of viruses to build a safer, more precise therapeutic future.
Includes cutting-edge techniques Provides step-by-step detail essential for reproducible results Contains key implementation advice from the experts
Autor*in
Horacio Bach
Themen in »Virus-Like Particles«
VLPs Structural biology Viral structural proteins Immune response Delivery vehicles Chemotherapeutics RNA vaccines Gene therapy